Yuri Stupel is son of Petar Stupel. He graduated from the Academy for Music and Dance Art in Plovdiv. In the 1970s he organised the band Association together with his fellows Haygashod Agassian, Kristian Boyadjiev and Georgi Denkov. With Haygashod Agassian he formed the duo Balgarche (Bulgarian Boy). He won recognition as pop music songwriter at the Youth Pop Song Competition where his song Hymn (performed by Biser Kirov) won the first prize in 1973 or when he won the prize of the Bulgarian National Television in 1978 for his song Sun (performed by the band Tonika).

In the 1980s he composed scores to over 250 TV serials (the serial Kliment Sings and Paints, etc.), theatre and puppet productions, some of which won national and international prizes. He also wrote the music score to several films including The Mooncalf, directed by Sergei Komitski (1987) and Night Rate, directed by Petar B. Vasilev (1987). He was commissioned works by prestigious theatres as the MHAT in Moscow, the theatres in Krakow and Thessaloniki. In Bulgaria he collaborated with Stefan Tzanev creating musical plays.

In the 1990s he settled in Thessaloniki, Greece where he joined the staff of the Jenny Karezi Conservatoire. In Greece and Cypress he composed music to theatre productions (more than 30) staged at the National Theatre in Athens, the Athenaeum Theatre, the State Theatre of North Greece in Thessaloniki, etc.

Musical plays:
Love Boulevards (1983, Youth Theatre; 1989, National Palace of Culture);
The Knight of the Rueful Countenance;
The Most Wonderful Wonder;
The Dwarf and the Seven Snow-Whites Plus One (libretto by Stefan Tzanev).

Film musical:
My Uncle Godfather (in co-authorship with Petar Stupel), directed by Stefan Dimitrov (1988).